We examined the potential benefits of carnitine and folic acid in reducing bone pain and fatigue in patients with beta-thalassemia minor. Over three months, 73 participants received either carnitine alone, a combination of carnitine and folic acid, or folic acid alone, while a control group went without supplementation.
Our results showed that carnitine significantly improved plasma levels and reduced bone pain and muscle weakness for those affected by this condition. Although folic acid improved red blood cell levels, its impact on bone pain was not directly highlighted. Overall, our findings suggest that carnitine can be beneficial in addressing bone pain in these patients.
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Most Useful Reviews
0
Negative effects experienced
276 people found this helpful
Initially thought a high dosage of B vitamins was beneficial, but I experienced dark yellow urine, pain in my bladder, strong weakness, and eventually liver pain. I regretted taking these vitamins thoughtlessly.
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9
Improved bone discomfort
10 people found this helpful
I'm very pleased with this product. The Solgar B complex is easy to swallow and I've found it effective. I suffered from fatigue and poor sleep, but they’ve improved since taking these vitamins. Additionally, my hair has stopped falling out, and I've noticed improvements in bone pain and my heart. It's an excellent support for the body during stressful periods, and there are no allergies or issues. I will definitely repurchase this complex.
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9
Pain elimination
8 people found this helpful
This product, along with vitamin C and glucosamine, helped alleviate my bone pain and restored flexibility to my joints and muscles. I bought it again after four years.
We examined the potential benefits of carnitine and folic acid in reducing bone pain and fatigue in patients with beta-thalassemia minor. Over three months, 73 participants received either carnitine alone, a combination of carnitine and folic acid, or folic acid alone, while a control group went without supplementation.
Our results showed that carnitine significantly improved plasma levels and reduced bone pain and muscle weakness for those affected by this condition. Although folic acid improved red blood cell levels, its impact on bone pain was not directly highlighted. Overall, our findings suggest that carnitine can be beneficial in addressing bone pain in these patients.
Read More
User Reviews
USERS' SCORE
Likely Ineffective
Based on 19 Reviews
4.6
All Reviews
Positive Reviews
Negative Reviews
0
Negative effects experienced
276 people found this helpful
Initially thought a high dosage of B vitamins was beneficial, but I experienced dark yellow urine, pain in my bladder, strong weakness, and eventually liver pain. I regretted taking these vitamins thoughtlessly.
Read More
9
Improved bone discomfort
10 people found this helpful
I'm very pleased with this product. The Solgar B complex is easy to swallow and I've found it effective. I suffered from fatigue and poor sleep, but they’ve improved since taking these vitamins. Additionally, my hair has stopped falling out, and I've noticed improvements in bone pain and my heart. It's an excellent support for the body during stressful periods, and there are no allergies or issues. I will definitely repurchase this complex.
Read More
9
Pain elimination
8 people found this helpful
This product, along with vitamin C and glucosamine, helped alleviate my bone pain and restored flexibility to my joints and muscles. I bought it again after four years.
Read More
9
Boosted energy levels
4 people found this helpful
For a long time, I suffered from impotence and lethargy, resulting in bone pain. I discovered a lack of B vitamins and ordered Solgar’s, which are high quality. Within a week, my energy increased, as did my motivation. I stopped feeling tired and my back pain diminished. My mood improved significantly too, although I had a flu episode. I believe multivitamins are essential for boosting immunity before continuing B vitamins.
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10
Pain-free movement
1 people found this helpful
I've suffered from back pain, particularly due to a spinal hernia, for many years. However, continuous use of this complex has provided pain-free movement and improved my overall vitality and confidence.
Bone pain is a discomfort or ache that originates within the bones themselves and can range from mild to severe. It is different from muscle or joint pain, as it directly affects the skeletal structure. Bone pain can be caused by a variety of factors, including injuries, medical conditions such as osteoarthritis or osteoporosis, infections, or tumors. Symptoms may vary depending on the underlying cause but often include a dull, penetrating ache that may worsen with movement or pressure.
If you're experiencing persistent bone pain, it’s essential to consult with a healthcare professional for a proper diagnosis and treatment plan. Imaging tests like X-rays, MRI, or CT scans may be utilized to determine the root cause of the pain. Treatment can vary widely, ranging from medications to alleviate pain and inflammation to physical therapy or, in some cases, surgical interventions. Understanding the underlying cause is crucial to effectively managing bone pain and ensuring the best path to recovery.
Vitamin B Complex refers to a group of water-soluble vitamins that play important roles in cell metabolism and overall health. This group typically includes eight essential vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). Each of these vitamins contributes uniquely to various bodily functions, such as energy production, red blood cell formation, and nervous system function. For instance, B12 and folate are crucial in preventing anemia, while B6 is vital for brain development and function.
Many people can obtain their daily requirements of B vitamins through a balanced diet that includes whole grains, meats, eggs, nuts, leafy greens, and dairy products. However, certain groups—like vegetarians, pregnant women, and older adults—may benefit from supplementation to meet their nutritional needs. It's important to consult with a healthcare professional before starting any supplement regimen, as excessive intake of certain B vitamins can lead to adverse effects. Overall, ensuring adequate intake of Vitamin B Complex is vital for maintaining energy levels and supporting overall health.
Based on user reviews, the timeline for experiencing relief from bone pain while taking the vitamin B complex varies, but many users report noticing positive effects within a week. For instance, one user mentioned feeling an increase in energy and a significant reduction in back pain within just seven days of introducing the supplement into their regimen Read Review. Similarly, another reviewer experienced joint pain reduction and overall improvements in wellbeing after one week of use Read Review.
However, some users suggest that continued use over a longer duration may lead to enhanced benefits. For example, another user indicated a substantial reduction in neck pain after a month of consistent intake, while a different review highlights that incorporating the complex seasonally for 1-1.5 months effectively relieved back pain and muscle tension Read ReviewRead Review. Overall, while initial results might be seen within a week, users recommend maintaining a consistent regimen to achieve sustained relief and benefits.
The supplement in question, carnitine, has shown promise in scientific research for alleviating bone pain, particularly in patients with beta-thalassemia minor. A study conducted with 73 participants indicated that carnitine significantly reduced bone pain and muscle weakness over a three-month period when compared to a control group that did not receive supplementation [1]. While folic acid, often administered alongside carnitine, demonstrated some benefits in improving red blood cell levels, its direct effect on bone pain was not emphasized in the research findings.
Based on user reviews, many individuals have reported notable improvements in symptoms after taking the vitamin B complex. A significant number of users experienced reductions in various types of pain, particularly bone, back, and joint pain. One user noted that after persistent use of the complex, they achieved pain-free movement, restoring their overall vitality and confidence Read Review. Another reviewer mentioned effective relief for both back pain and muscle tension, which enhanced their endurance and brain function Read Review. Further, a user highlighted a marked improvement in bone pain, which disappeared after they identified a deficiency that the product addressed Read Review.
In addition to pain relief, users reported enhancements in energy levels, mood, and overall wellbeing. One user shared that within a week of taking the complex, they felt more energized, less anxious, and noticed a decline in joint pain and mood swings Read Review. However, it is important to note that individual results may vary, and a few users did experience adverse effects, emphasizing the need for careful dosage and monitoring. Overall, while many found relief from their symptoms, others highlighted the necessity of consistent use to maintain benefits Read Review.
Based on user reviews, many individuals report positive outcomes when combining the vitamin B complex with other supplements for managing bone pain. Notably, one user mentioned that taking the complex alongside vitamin C and glucosamine significantly helped alleviate their bone pain and restored flexibility in their joints and muscles Read Review. Additionally, another reviewer praised the supplement's effectiveness in dealing with arthritis-related bone pain, stating that pairing it with flaxseed oil almost eliminated their discomfort entirely Read Review.
Furthermore, users have highlighted the importance of consistent use for sustained benefits. For instance, one user reported a complete disappearance of their bone pain, initially caused by a deficiency, after incorporating the B complex into their routine Read Review. This feedback suggests that including the vitamin B complex in a broader supplement regimen, particularly when addressing bone pain, can enhance overall effectiveness and promote long-term relief.
Users report varying experiences when it comes to finding the right dosage of Vitamin B Complex for treating bone pain. Some users have noted substantial improvements in their bone pain and overall vitality with consistent use of a B complex. For instance, one user experienced a "significant reduction in inflammation and pain" in their knees after taking the Solgar B complex, which they used alongside flaxseed oil for better effectiveness Read Review. Another user highlighted that their bone pain, which stemmed from a deficiency, vanished after using the product, suggesting the importance of proper dosage in addressing specific health concerns Read Review.
Conversely, some users reported adverse effects from high dosages, such as a user who experienced dark yellow urine and bladder pain after taking a high dose Read Review. It seems consistency and the right dosage are crucial, as another user with hypothyroidism mentioned that missing doses would lead to a return of their symptoms, emphasizing that regular intake is necessary for ongoing relief from bone pain Read Review. Ultimately, while many users found relief at therapeutic doses, caution with high dosages is advised.
9
Boosted energy levels
4 people found this helpful
For a long time, I suffered from impotence and lethargy, resulting in bone pain. I discovered a lack of B vitamins and ordered Solgar’s, which are high quality. Within a week, my energy increased, as did my motivation. I stopped feeling tired and my back pain diminished. My mood improved significantly too, although I had a flu episode. I believe multivitamins are essential for boosting immunity before continuing B vitamins.
7.5
Less joint pain
3 people found this helpful
I was anxious about joint pains and headaches, which led to a depressive state. After a week of taking these vitamins, I noticed joint pain decreasing and mood swings disappeared. I feel energised, and these Solgar vitamins support heart and nervous system health. They contain no wheat or dairy products and are gluten-free. The quality is exceptional, and I wish everyone good luck with their health.
7.5
Stronger nails
2 people found this helpful
I must note that the dosages in this complex are therapeutic, making it more of a medicine than a vitamin. After a month of use, my neck pain subsided, and I also noticed stronger nails and improved hair growth. Good product; I will continue taking it.
7.5
Less muscle tension
2 people found this helpful
I’m ordering this vitamin B complex for the third time. They effectively relieve back pain and muscle tension, while enhancing endurance and brain function. Initially, the high doses seemed daunting, but I realised this treatment was necessary. I take them seasonally for 1-1.5 months.
10
Pain-free movement
1 people found this helpful
I've suffered from back pain, particularly due to a spinal hernia, for many years. However, continuous use of this complex has provided pain-free movement and improved my overall vitality and confidence.
9
Joint pain relief
All Solgar products are of excellent quality. The pill size is standard. After taking these vitamins, my bone pain, caused by a deficiency, has disappeared. Thank you, iHerb!
6
Increased energy
1 people found this helpful
I have hypothyroidism and have found that taking these vitamins has alleviated my body pain considerably; I even managed to go shopping! However, missing doses leads to a return of symptoms and body pain. Consistency is key.
9
Pain elimination
8 people found this helpful
This product, along with vitamin C and glucosamine, helped alleviate my bone pain and restored flexibility to my joints and muscles. I bought it again after four years.
8
Reduced bone pain
11 people found this helpful
Great anti-inflammatory! I mainly use this product for my joints. As someone who is overweight and has arthritis, I often experience bone pain. This B complex formula from Solgar significantly reduces inflammation and pain, especially in my knees. I take it with flaxseed oil, which almost eliminates the pain entirely. I prefer this natural alternative to OTC pain relievers, as I believe they harm your liver or kidneys. The 100 B complex lasts longer too!
0
Negative effects experienced
276 people found this helpful
Initially thought a high dosage of B vitamins was beneficial, but I experienced dark yellow urine, pain in my bladder, strong weakness, and eventually liver pain. I regretted taking these vitamins thoughtlessly.
7
Carnitine aids bone pain relief
Determining and surveying the role of carnitine and folic acid to decrease fatigue in β-thalassemia minor subjects.
We examined the potential benefits of carnitine and folic acid in reducing bone pain and fatigue in patients with beta-thalassemia minor. Over three months, 73 participants received either carnitine alone, a combination of carnitine and folic acid, or folic acid alone, while a control group went without supplementation.
Our results showed that carnitine significantly improved plasma levels and reduced bone pain and muscle weakness for those affected by this condition. Although folic acid improved red blood cell levels, its impact on bone pain was not directly highlighted. Overall, our findings suggest that carnitine can be beneficial in addressing bone pain in these patients.
References
Tabei SM, Mazloom M, Shahriari M, Zareifar S, Azimi A, et al. Determining and surveying the role of carnitine and folic acid to decrease fatigue in β-thalassemia minor subjects. Pediatr Hematol Oncol. 2013;30:742. 10.3109/08880018.2013.771388